Screen Resolution and Windowed Mode

Running in Windowed Mode
Since the game is locked to full screen mode, to run the game in a Window requires a third party tool DxWnd once you've downloaded and extracted it, and run dxwnd.exe Go to File->Import... browse to the DxWnd exports folder and open Disney Infinity 3.0.dxw

You should see an icon appear in the window Right-Click->Modify and set Path to the correct game exe location (C:\Steam\steamapps\common\Disney Infinity 3.0 Gold Edition\DisneyInfinity3.exe), and click OK Double-click the icon to run the game.

There have been some reports of this not working in the DxWnd forum. Also the game will minimise if you switch focus to another window, which you can avoid - in the Modify screen of DxWnd by setting the No notify option, however the keyboard focus will be shared with DI and other windows so you may get odd side-effects.

Hacking Alternative Screen Resolutions
See the Wide Screen Gaming Forum guide

VR Support
See the Helix Mod guide